The Biological Supremacy of Immunotherapy (ReVival)
Cancer is an aggressive disease, and an even greater treatment is needed to overcome the complexity of disease. The treatment is known as Immunotherapy (Revival) and it potentially offer patients a hope to eradicate it permanently. At Revine Clinic, the treatment has changed the lives of many people for the better. Let’s explore this article.
Cancer Treatment
Cancer treatment refers to the medical strategy to diagnose, manage, and cure cancer. When it comes to treatment options, giving the choices are as diverse as the types of cancer. Each treatment serves the same purpose, but the execution method vary like their efficiency too.
- Surgery: Surgical procedures involve the operation to remove tumors or affected tissues.
- Chemotherapy: Chemotherapy uses drugs to kill or slow the growth of cancer cells. It can be administered orally, intravenously, or directly into the affected area. This is a common treatment for localized and metastatic cancers.
- Radiation Therapy: Radiation therapy involves using high-energy rays to target and kill cancer cells. The treatment is preferred for tumor reduction before surgery, eliminate remaining cancer cells after surgery, or manage pain.
- Targeted Therapy: Targeted therapies focus on specific molecular changes that stimulates cancer growth. The goal is to block the signals that promote tumor growth while avoiding damage to healthy cells.
- Hormone Therapy: In certain cancer types such as breast and prostate cancers which are hormone-sensitive, the hormone therapy is used to treat them. It involves blocking hormones or interfering with their effects to slow or stop cancer growth.
- Stem Cell Transplant: Stem cell transplantation is utilized to replace damaged bone marrow with healthy stem cells. It’s often used in treating blood-related cancers like leukemia and lymphoma.
Top 5 cancer in Malaysia & Its Survival Rate
Breast Cancer
Breast cancer is a type of cancer that originates in the cells of the breast tissue. It is the most common cancer diagnosed in women worldwide, and it can also affect men although it is rare. For localized (early-stage) breast cancer, the survival rate is relatively high, around 80-90% or more. However, the rate decreases as the cancer advances, and it goes down to 23.3% at Stage 4
Colon Cancer
Colon cancer, also known as colorectal cancer, is a type of cancer that originates in the colon or rectum, which are parts of the digestive system. It typically start with the growth of abnormal cells named polyps. Localized colon cancer has a survival rate of around 80%, while the rate decreases for more advanced stages. The survival rate is around 18.8% at Stage 4.
Lung Cancer
Lung cancer is a type of cancer that begins in the cells of the lungs. It is one of the deadliest forms of cancer worldwide and affects smokers and non-smokers alike. Lung cancer survival rates are generally lower, especially for advanced stages. The survival rate for lung cancer starts from around 38% and it declines to 6.3% at Stage 4.
Lymphoma Cancer
Lymphoma is a type of cancer that originates in the lymphatic system, which is a part of the body’s immune system. The survival rates start at 60-62% but it declines by half to around 35.5% at Stage 4.
Nasopharyngeal Cancer
Nasopharyngeal cancer is a type of cancer that originates in the nasopharynx, which is the upper part of the throat located behind the nose. The survival rate for nasopharyngeal cancer in Malaysia ranges from around 60-70% for localized cases, but it lowers to 26.9% at Stage 4.
The Breakthrough in Cancer Treatment - cancer Immunotherapy
The advance of cancer research in the past two decades gives way to immunotherapy. Cancer immunotherapy activates the immune system to prevent, control, and eliminate tumour cells. Despite the best treatment, the cancer cells can evolve and evade the immune system for continued growth. They may develop these adaptations to avoid eradication:
- Have genetic changes to mask themselves from the immune system
- Have protein on their surfaces to turn off immune cells
- Alter the normal cells around the tumour to interfere with how immune system attack the cancer cells
Immunology aims to strengthen the immune system to identify and destroy the cancer cells with pinpoint accuracy. The treatment overall enhances the functionality of the immune system to ease the identification of cancer cells as targets.
The Biological Supremacy of Immunotherapy
Immunotherapy can be personalized to deliver even greater potency on the affected areas. The treatment would uses Peripheral blood mononuclear cells (PBMCs) to as the key instigator. The idea is to harness the power of T cells to recognize and attack cancer cells more effectively. The PBMCs will be expanded for the CIK cells which are later reinfused into the patient. It would enhance the immune system to take on the cancer cells more aggressively.
Cancer Immunotherapy (ReVival) Therapy Procedure
- Autologous: The cells are extracted from the patient’s blood.
- No Risk of Immune Rejection: Due to the same genetic make-up of the blood, there is no chance of complications when the cells are reinfused to the body.
- No Side Effect: The treatment can be done precisely on the cancerous part to preserve the healthy cells.
- Safe and Natural: No genetic manipulation because all cells are produced naturally with no addition of foreign substances.
- Work In Sync with Conventional Treatment: Immunotherapy can work well together to enhance the outcomes of treatment
- High Performance: The treatment is clinically proven to work.
Cancer Immunotherapy (ReVival) Production Flow
The flow of the treatment can be divided into 5 phases.
- Blood withdrawal: An average amount of 150-200ml will be collected from the patient. The goal is to extract immune cells, typically T cells, from the patient’s blood.
- Leukapheresis: The blood is separated into its various components. The white blood cells, particularly lymphocytes, are selectively collected and isolated from the rest of the blood components.
- Cells Activation: The collected cells will be activated through various methods such as antigen presentation, co-simulation, genetic modification, and others. The goal is to enhance their ability to respond to specific antigens (proteins) present on the surface of cancer cells.
- Cells Expansion: The mmune cells are encouraged to multiply, leading to an increased number of activated cells. This expansion step aims to generate a sufficient number of activated cells for therapeutic use.
- Cells Infusion: When the production has created sufficient amount of cells, they can be infused back into the patient’s body. The cells will proceed to target and attack cancer cells.
Cancer Immunotherapy (ReVival) Protocol Strategy
Approximately 150-200ml of blood will be collected from the patient. Once completed, the immune cells extracted from the blood will enter a culture period. In the culture period, the cells will enter activation and expansion phase. The purpose is to enhance the efficiency of the cells and increase the amount of usable cells. The expansion stops when the target of 10 billion cells per transfusion is reached. The treatment length spans up to 6 weeks with one infusion per week.
How Immunotherapy (ReVival) Difference From Conventional Cancer Treatment
Case Study About Effectiveness & Efficacy of Cytokine-induced killer (CIK) Immunotherapy
In a 5-year study of CIK and control group for breast cancer, it is found that the CIK group has a higher survival rate between 80-90%. In contrast, the control group only scored around 73%. In addition, the unlikelihood of recurrence for CIK group peaked at 77% whereas the control group only hit 68%.
Moreover, when the immunotherapy is combined with chemotherapy, the CIK group has a survival rate of 78% whereas the control group only reach 42% in the third year of post-cancer free life. As a whole, the case study shows that the CIK immunotherapy kill cancer better for increased survival rate and it complements existing treatments as well.
Consult with Revine Clinic to Get more information about Immunotherapy (ReVival)
Cancer is not the end. Even when the conventional treatments may struggle to show results, the Revival therapy offers a good chance to turn things around. The immunotherapy has been widely studied and the results are clinically proven to help patients overcome the challenges. Book a consultation today at Revine Clinic to evaluate if immunotherapy is right for you.
FAQs
Is immunotherapy as strong as chemotherapy?
Immunotherapy and chemotherapy are distinct cancer treatments with different mechanisms of action. However, immunotherapy do not kill healthy cells and there are no noticeable side effects which makes it more tolerable.
What stage of cancer is immunotherapy used?
Immunotherapy can be used in various stages of cancer, including advanced stages, where it has shown effectiveness in boosting the immune system to target and attack cancer cells.
Can cancer be cured with immunotherapy?
Yes, clinical studies have shown that cancer can be cured with the treatment alone or in conjunction with other conventional treatments.
How successful is immunotherapy for cancer?
In general, the chances are high. However, the success of immunotherapy for cancer varies widely depending on factors such as the type of cancer, the patient’s individual characteristics, and the specific immunotherapy approach being used.